WATCH: George Lopez's Best Celebrity Interviews!

Happy birthday, George Lopez! In celebration of Lopez's grand born day, we are taking a look at some of his funniest celebrity interviews ever:

MORE: George Lopez Mistaken for Housekeeper at NYC hotel

1. Matthew McConaughey

Not only is Matthew McConaughey super hot, but he also loves Latinas! In 2011, the actor surprised everyone when he spoke Spanish on Lopez Tonight.

2. Constance Marie

Believe it or not, Constance Marie almost didn't get the role of Angie Lopez on George Lopez. The 49-year-old was competing against an actress with big boobs. Thankfully, Marie ended up getting the role on the successful series that aired for six seasons. I guess big boobs aren't everything! Watch what happens when the two former co-stars come together.

3. Kevin Hart

There is no doubt Kevin Hart is one of the funniest guys out there. The comedian stopped by The George Lopez Show and joked about his 3-year-old son thinking he was really Spider-Man. Watch!

4. Cameron Diaz

The Cubana definitely has a sense of humor. Cameron Diaz appeared on Lopez Tonight and talked about her crazy high school experience. The actress revealed that not only did she go to school with Snoop Dogg, but she also claims to have bought marijuana from the rapper.

5. Anthony Anderson

If you've never watched Anthony Anderson on The George Lopez Show, drop what you’re doing and watch it. The comedian stopped by the show and shared some hilarious stories like stealing from his mother and his daughter thinking she was pregnant.

6. Pitbull

Pitbull appeared on Lopez Tonight to discuss his new album Planet Pit and his covers for Latina and Rolling Stone. George Lopez told the 34-year-old singer he struggled to find his Latina issue because it was sold out everywhere. The singer jokingly responded, “That’s because me, my mother, and abuelita bought them all.”